Cargando…
Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin
Afamin, which is a human blood plasma glycoprotein, a putative multifunctional transporter of hydrophobic molecules and a marker for metabolic syndrome, poses multiple challenges for crystallographic structure determination, both practically and in analysis of the models. Several hundred crystals we...
Autores principales: | Naschberger, Andreas, Juyoux, Pauline, von Velsen, Jill, Rupp, Bernhard, Bowler, Matthew W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889915/ https://www.ncbi.nlm.nih.gov/pubmed/31793901 http://dx.doi.org/10.1107/S2059798319013500 |
Ejemplares similares
-
The N14 anti-afamin antibody Fab: a rare V(L)1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling
por: Naschberger, Andreas, et al.
Publicado: (2016) -
Afamin: an early predictor of preeclampsia
por: Köninger, Angela, et al.
Publicado: (2018) -
Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse
por: Weiss, Alexander K.H., et al.
Publicado: (2020) -
Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin
por: Mihara, Emiko, et al.
Publicado: (2016) -
Evaluation of first- and third-trimester afamin levels in preeclampsia
por: Gülücü, Selim, et al.
Publicado: (2023)