NR4A1 promotes TNF-α-induced chondrocyte death and migration injury via activating the AMPK/Drp1/mitochondrial fission pathway

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Nuclear receptor subfamily 4 group A member 1 (NR4A1)-induced chondrocyte death plays a critical role in the development of osteoarthritis through poorly defined mechanisms. The present study aimed to investigate the role of NR4A1 in regulating chondrocyte death in response to tumor necrosis factor-...

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Detalles Bibliográficos
Autores principales: Zheng, Zhibo, Xiang, Shuai, Wang, Yingjie, Dong, Yulei, Li, Zeng, Xiang, Yongbo, Bian, Yanyan, Feng, Bin, Yang, Bo, Weng, Xisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889925/
https://www.ncbi.nlm.nih.gov/pubmed/31746366
http://dx.doi.org/10.3892/ijmm.2019.4398
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