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Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
INTRODUCTION: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs. CASE PRESENTATION: A 70-year-old female with retropharyngeal abscess developed feature...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890189/ https://www.ncbi.nlm.nih.gov/pubmed/31819670 http://dx.doi.org/10.2147/IMCRJ.S218895 |
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author | Pokharel, Apar Basnet, Prabhat Sharma, Bibek Thapa, Kripesh |
author_facet | Pokharel, Apar Basnet, Prabhat Sharma, Bibek Thapa, Kripesh |
author_sort | Pokharel, Apar |
collection | PubMed |
description | INTRODUCTION: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs. CASE PRESENTATION: A 70-year-old female with retropharyngeal abscess developed features of Lemierre syndrome. The condition was managed with serial aspiration of the abscess and prolonged usage of intravenous antibiotics. DISCUSSION: Lemierre syndrome is most frequently caused by the anaerobic bacterium, Fusobacterium necrophorum. Although rare, there is evidence of a resurgence in the condition in recent years, most probably due to reduced use of antibiotic therapy for sore throats. Although there is a characteristic clinical picture, many clinicians are unaware of this condition, leading to delayed diagnosis with potentially fatal consequences. CONCLUSION: Early diagnosis of this condition and prompt treatment with intravenous broad spectrum antibiotics results in a complete resolution of this condition. Surgery is indicated in the case of abscess formation. |
format | Online Article Text |
id | pubmed-6890189 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-68901892019-12-09 Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature Pokharel, Apar Basnet, Prabhat Sharma, Bibek Thapa, Kripesh Int Med Case Rep J Case Report INTRODUCTION: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs. CASE PRESENTATION: A 70-year-old female with retropharyngeal abscess developed features of Lemierre syndrome. The condition was managed with serial aspiration of the abscess and prolonged usage of intravenous antibiotics. DISCUSSION: Lemierre syndrome is most frequently caused by the anaerobic bacterium, Fusobacterium necrophorum. Although rare, there is evidence of a resurgence in the condition in recent years, most probably due to reduced use of antibiotic therapy for sore throats. Although there is a characteristic clinical picture, many clinicians are unaware of this condition, leading to delayed diagnosis with potentially fatal consequences. CONCLUSION: Early diagnosis of this condition and prompt treatment with intravenous broad spectrum antibiotics results in a complete resolution of this condition. Surgery is indicated in the case of abscess formation. Dove 2019-11-29 /pmc/articles/PMC6890189/ /pubmed/31819670 http://dx.doi.org/10.2147/IMCRJ.S218895 Text en © 2019 Pokharel et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Pokharel, Apar Basnet, Prabhat Sharma, Bibek Thapa, Kripesh Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature |
title | Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature |
title_full | Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature |
title_fullStr | Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature |
title_full_unstemmed | Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature |
title_short | Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature |
title_sort | lemierre syndrome. a forgotten disease. case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890189/ https://www.ncbi.nlm.nih.gov/pubmed/31819670 http://dx.doi.org/10.2147/IMCRJ.S218895 |
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