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Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature

INTRODUCTION: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs. CASE PRESENTATION: A 70-year-old female with retropharyngeal abscess developed feature...

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Autores principales: Pokharel, Apar, Basnet, Prabhat, Sharma, Bibek, Thapa, Kripesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890189/
https://www.ncbi.nlm.nih.gov/pubmed/31819670
http://dx.doi.org/10.2147/IMCRJ.S218895
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author Pokharel, Apar
Basnet, Prabhat
Sharma, Bibek
Thapa, Kripesh
author_facet Pokharel, Apar
Basnet, Prabhat
Sharma, Bibek
Thapa, Kripesh
author_sort Pokharel, Apar
collection PubMed
description INTRODUCTION: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs. CASE PRESENTATION: A 70-year-old female with retropharyngeal abscess developed features of Lemierre syndrome. The condition was managed with serial aspiration of the abscess and prolonged usage of intravenous antibiotics. DISCUSSION: Lemierre syndrome is most frequently caused by the anaerobic bacterium, Fusobacterium necrophorum. Although rare, there is evidence of a resurgence in the condition in recent years, most probably due to reduced use of antibiotic therapy for sore throats. Although there is a characteristic clinical picture, many clinicians are unaware of this condition, leading to delayed diagnosis with potentially fatal consequences. CONCLUSION: Early diagnosis of this condition and prompt treatment with intravenous broad spectrum antibiotics results in a complete resolution of this condition. Surgery is indicated in the case of abscess formation.
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spelling pubmed-68901892019-12-09 Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature Pokharel, Apar Basnet, Prabhat Sharma, Bibek Thapa, Kripesh Int Med Case Rep J Case Report INTRODUCTION: Lemierre syndrome is a serious condition that associates oropharyngeal infection and thrombosis of the internal jugular vein (IJV) with subsequent distant septic emboli, most frequently in the lungs. CASE PRESENTATION: A 70-year-old female with retropharyngeal abscess developed features of Lemierre syndrome. The condition was managed with serial aspiration of the abscess and prolonged usage of intravenous antibiotics. DISCUSSION: Lemierre syndrome is most frequently caused by the anaerobic bacterium, Fusobacterium necrophorum. Although rare, there is evidence of a resurgence in the condition in recent years, most probably due to reduced use of antibiotic therapy for sore throats. Although there is a characteristic clinical picture, many clinicians are unaware of this condition, leading to delayed diagnosis with potentially fatal consequences. CONCLUSION: Early diagnosis of this condition and prompt treatment with intravenous broad spectrum antibiotics results in a complete resolution of this condition. Surgery is indicated in the case of abscess formation. Dove 2019-11-29 /pmc/articles/PMC6890189/ /pubmed/31819670 http://dx.doi.org/10.2147/IMCRJ.S218895 Text en © 2019 Pokharel et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Pokharel, Apar
Basnet, Prabhat
Sharma, Bibek
Thapa, Kripesh
Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
title Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
title_full Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
title_fullStr Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
title_full_unstemmed Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
title_short Lemierre Syndrome. A Forgotten Disease. Case Report and Review of Literature
title_sort lemierre syndrome. a forgotten disease. case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890189/
https://www.ncbi.nlm.nih.gov/pubmed/31819670
http://dx.doi.org/10.2147/IMCRJ.S218895
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