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Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report

RATIONALE: Bladder cancer (BC) is commonly diagnosed in the urinary system and the most common subtype is transitional urothelial carcinoma (TCC). Even with the best treatment, tumor recurrence and metastases always occur. While clinicians commonly observe the metastases to pelvic lymph nodes, liver...

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Autores principales: Wu, Kaijie, Fan, Junjie, Liang, Hua, Yao, Yu, He, Dalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890337/
https://www.ncbi.nlm.nih.gov/pubmed/31770212
http://dx.doi.org/10.1097/MD.0000000000018000
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author Wu, Kaijie
Fan, Junjie
Liang, Hua
Yao, Yu
He, Dalin
author_facet Wu, Kaijie
Fan, Junjie
Liang, Hua
Yao, Yu
He, Dalin
author_sort Wu, Kaijie
collection PubMed
description RATIONALE: Bladder cancer (BC) is commonly diagnosed in the urinary system and the most common subtype is transitional urothelial carcinoma (TCC). Even with the best treatment, tumor recurrence and metastases always occur. While clinicians commonly observe the metastases to pelvic lymph nodes, liver, lung, and bone, it may infrequently spread to some uncommon locations. PATIENT CONCERNS: The patient was a 67-year-old man with a diagnosis of high-grade TCC with squamous differentiation in the bladder and prostate. Subsequently, radical cystoprostatectomy, adjuvant radiotherapy, and chemotherapy were performed. However, he felt intermittent right scrotal pain about 1 year later. DIAGNOSIS: Ultrasound strongly suggested a testicular neoplasm of right testis, but the left was normal. INTERVENTIONS: The patient underwent a right radical orchiectomy and histopathology confirmed testicular metastatic neoplasm from bladder. Moreover, further examination with positron emission tomography revealed no visible distant spread of the urothelial carcinoma. OUTCOMES: No signs of tumor recurrence or distant metastasis were visible under follow-up 1 year after radical orchiectomy. LESSONS: Testicular mass may be metastatic tumor during follow-up for patients who were diagnosed as BC, especially for TCC with variant histology. The reason of this could be explained of residual micrometastases after surgery and need more examination to discover local micrometastases to apply more aggressive treatment.
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spelling pubmed-68903372020-01-22 Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report Wu, Kaijie Fan, Junjie Liang, Hua Yao, Yu He, Dalin Medicine (Baltimore) 7300 RATIONALE: Bladder cancer (BC) is commonly diagnosed in the urinary system and the most common subtype is transitional urothelial carcinoma (TCC). Even with the best treatment, tumor recurrence and metastases always occur. While clinicians commonly observe the metastases to pelvic lymph nodes, liver, lung, and bone, it may infrequently spread to some uncommon locations. PATIENT CONCERNS: The patient was a 67-year-old man with a diagnosis of high-grade TCC with squamous differentiation in the bladder and prostate. Subsequently, radical cystoprostatectomy, adjuvant radiotherapy, and chemotherapy were performed. However, he felt intermittent right scrotal pain about 1 year later. DIAGNOSIS: Ultrasound strongly suggested a testicular neoplasm of right testis, but the left was normal. INTERVENTIONS: The patient underwent a right radical orchiectomy and histopathology confirmed testicular metastatic neoplasm from bladder. Moreover, further examination with positron emission tomography revealed no visible distant spread of the urothelial carcinoma. OUTCOMES: No signs of tumor recurrence or distant metastasis were visible under follow-up 1 year after radical orchiectomy. LESSONS: Testicular mass may be metastatic tumor during follow-up for patients who were diagnosed as BC, especially for TCC with variant histology. The reason of this could be explained of residual micrometastases after surgery and need more examination to discover local micrometastases to apply more aggressive treatment. Wolters Kluwer Health 2019-11-27 /pmc/articles/PMC6890337/ /pubmed/31770212 http://dx.doi.org/10.1097/MD.0000000000018000 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 7300
Wu, Kaijie
Fan, Junjie
Liang, Hua
Yao, Yu
He, Dalin
Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report
title Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report
title_full Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report
title_fullStr Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report
title_full_unstemmed Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report
title_short Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report
title_sort rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: a case report
topic 7300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890337/
https://www.ncbi.nlm.nih.gov/pubmed/31770212
http://dx.doi.org/10.1097/MD.0000000000018000
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