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Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma

PURPOSE: Glucocorticoid (GC)–induced ocular hypertension (GC-OHT) is a serious side effect of prolonged GC therapy that can lead to glaucoma and permanent vision loss. GCs cause a plethora of changes in the trabecular meshwork (TM), an ocular tissue that regulates intraocular pressure (IOP). GCs act...

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Detalles Bibliográficos
Autores principales:	Patel, Gaurang C., Millar, J. Cameron, Clark, Abbot F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890434/ https://www.ncbi.nlm.nih.gov/pubmed/31050723 http://dx.doi.org/10.1167/iovs.18-26383

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