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Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors

Mutually exclusive KIT and PDGFRA mutations are considered to be the earliest events in gastrointestinal stromal tumors (GIST), but insufficient for their malignant progression. Herein, we aimed to identify driver genes and signaling pathways relevant to GIST progression. We investigated genetic pro...

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Detalles Bibliográficos
Autores principales:	Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizawa, Masakuni, Akiyama, Yasuto, Kusuhara, Masatoshi, Mochizuki, Tohru, Sugino, Takashi, Shiomi, Akio, Tsubosa, Yasuhiro, Uesaka, Katsuhiko, Terashima, Masanori, Yamaguchi, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890443/ https://www.ncbi.nlm.nih.gov/pubmed/31553483 http://dx.doi.org/10.1111/cas.14202

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