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Novel human Ab against vascular endothelial growth factor receptor 2 shows therapeutic potential for leukemia and prostate cancer

Vascular endothelial growth factor receptor 2 (VEGFR2) is highly expressed in tumor‐associated endothelial cells, where it modulates tumor‐promoting angiogenesis, and it is also found on the surface of tumor cells. Currently, there are no Ab therapeutics targeting VEGFR2 approved for the treatment o...

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Detalles Bibliográficos
Autores principales: Lu, Ruei‐Min, Chiu, Chiung‐Yi, Liu, I‐Ju, Chang, Yu‐Ling, Liu, Yaw‐Jen, Wu, Han‐Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890446/
https://www.ncbi.nlm.nih.gov/pubmed/31578782
http://dx.doi.org/10.1111/cas.14208