Chronic muscle weakness and mitochondrial dysfunction in the absence of sustained atrophy in a preclinical sepsis model

Chronic critical illness is a global clinical issue affecting millions of sepsis survivors annually. Survivors report chronic skeletal muscle weakness and development of new functional limitations that persist for years. To delineate mechanisms of sepsis-induced chronic weakness, we first surpassed...

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Detalles Bibliográficos
Autores principales: Owen, Allison M, Patel, Samir P, Smith, Jeffrey D, Balasuriya, Beverly K, Mori, Stephanie F, Hawk, Gregory S, Stromberg, Arnold J, Kuriyama, Naohide, Kaneki, Masao, Rabchevsky, Alexander G, Butterfield, Timothy A, Esser, Karyn A, Peterson, Charlotte A, Starr, Marlene E, Saito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890461/
https://www.ncbi.nlm.nih.gov/pubmed/31793435
http://dx.doi.org/10.7554/eLife.49920

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