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Analysis of stochastic fluctuations in responsiveness is a critical step toward personalized anesthesia
Traditionally, drug dosing is based on a concentration-response relationship estimated in a population. Yet, in specific individuals, decisions based on the population-level effects frequently result in over or under-dosing. Here, we interrogate the relationship between population-based and individu...
Autores principales: | McKinstry-Wu, Andrew R, Wasilczuk, Andrzej Z, Harrison, Benjamin A, Bedell, Victoria M, Sridharan, Mathangi J, Breig, Jayce J, Pack, Michael, Kelz, Max B, Proekt, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890463/ https://www.ncbi.nlm.nih.gov/pubmed/31793434 http://dx.doi.org/10.7554/eLife.50143 |
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