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Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure
AIMS/HYPOTHESIS: Exposure to environmental pollution has been consistently linked to diabetes incidence in humans, but the potential causative mechanisms remain unclear. Given the critical role of regulated insulin secretion in maintaining glucose homeostasis, environmental chemicals that reach the...
Autores principales: | Ibrahim, Muna, MacFarlane, Erin M., Matteo, Geronimo, Hoyeck, Myriam P., Rick, Kayleigh R. C., Farokhi, Salar, Copley, Catherine M., O’Dwyer, Shannon, Bruin, Jennifer E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890627/ https://www.ncbi.nlm.nih.gov/pubmed/31776611 http://dx.doi.org/10.1007/s00125-019-05035-0 |
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