Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 Å resolution

Specimens below 50 kDa have generally been considered too small to be analyzed by single-particle cryo-electron microscopy (cryo-EM). The high flexibility of pure RNAs makes it difficult to obtain high-resolution structures by cryo-EM. In bacteria, riboswitches regulate sulfur metabolism through bin...

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Detalles Bibliográficos
Autores principales: Zhang, Kaiming, Li, Shanshan, Kappel, Kalli, Pintilie, Grigore, Su, Zhaoming, Mou, Tung-Chung, Schmid, Michael F., Das, Rhiju, Chiu, Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890682/
https://www.ncbi.nlm.nih.gov/pubmed/31796736
http://dx.doi.org/10.1038/s41467-019-13494-7

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