Meglumine acridone acetate, the ionic salt of CMA and N-methylglucamine, induces apoptosis in human PBMCs via the mitochondrial pathway

Meglumine acridone acetate (MA) is used in Russia for the treatment of influenza and other acute respiratory viral infections. It was assumed, until recently, that its antiviral effect was associated with its potential ability to induce type I interferon. Advanced studies, however, have shown the fa...

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Detalles Bibliográficos
Autores principales: Plotnikova, Marina A., Klotchenko, Sergey A., Kiselev, Artem A., Gorshkov, Andrey N., Shurygina, Anna-Polina S., Vasilyev, Kirill A., Uciechowska-Kaczmarzyk, Urszula, Samsonov, Sergey A., Kovalenko, Alexey L., Vasin, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890692/
https://www.ncbi.nlm.nih.gov/pubmed/31796757
http://dx.doi.org/10.1038/s41598-019-54208-9

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