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Apolipoprotein E deficient rats generated via zinc-finger nucleases exhibit pronounced in-stent restenosis
The long-term success of coronary stent implantation is limited by in-stent restenosis (ISR). In spite of a broad variety of animal models available, an ideal high-throughput model of ISR has been lacking. Apolipoprotein E (apoE) deficient rats enable the evaluation of human-sized coronary stents wh...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890749/ https://www.ncbi.nlm.nih.gov/pubmed/31796798 http://dx.doi.org/10.1038/s41598-019-54541-z |