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Apolipoprotein E deficient rats generated via zinc-finger nucleases exhibit pronounced in-stent restenosis

The long-term success of coronary stent implantation is limited by in-stent restenosis (ISR). In spite of a broad variety of animal models available, an ideal high-throughput model of ISR has been lacking. Apolipoprotein E (apoE) deficient rats enable the evaluation of human-sized coronary stents wh...

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Detalles Bibliográficos
Autores principales: Cornelissen, Anne, Simsekyilmaz, Sakine, Liehn, Elisa, Rusu, Mihaela, Schaaps, Nicole, Afify, Mamdouh, Florescu, Roberta, Almalla, Mohammad, Borinski, Mauricio, Vogt, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890749/
https://www.ncbi.nlm.nih.gov/pubmed/31796798
http://dx.doi.org/10.1038/s41598-019-54541-z