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Estimating heritability and genetic correlations from large health datasets in the absence of genetic data
Typically, estimating genetic parameters, such as disease heritability and between-disease genetic correlations, demands large datasets containing all relevant phenotypic measures and detailed knowledge of family relationships or, alternatively, genotypic and phenotypic data for numerous unrelated i...
Autores principales: | Jia, Gengjie, Li, Yu, Zhang, Hanxin, Chattopadhyay, Ishanu, Boeck Jensen, Anders, Blair, David R., Davis, Lea, Robinson, Peter N., Dahlén, Torsten, Brunak, Søren, Benson, Mikael, Edgren, Gustaf, Cox, Nancy J., Gao, Xin, Rzhetsky, Andrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890770/ https://www.ncbi.nlm.nih.gov/pubmed/31796735 http://dx.doi.org/10.1038/s41467-019-13455-0 |
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