Estimating heritability and genetic correlations from large health datasets in the absence of genetic data

Typically, estimating genetic parameters, such as disease heritability and between-disease genetic correlations, demands large datasets containing all relevant phenotypic measures and detailed knowledge of family relationships or, alternatively, genotypic and phenotypic data for numerous unrelated i...

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Detalles Bibliográficos
Autores principales: Jia, Gengjie, Li, Yu, Zhang, Hanxin, Chattopadhyay, Ishanu, Boeck Jensen, Anders, Blair, David R., Davis, Lea, Robinson, Peter N., Dahlén, Torsten, Brunak, Søren, Benson, Mikael, Edgren, Gustaf, Cox, Nancy J., Gao, Xin, Rzhetsky, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890770/
https://www.ncbi.nlm.nih.gov/pubmed/31796735
http://dx.doi.org/10.1038/s41467-019-13455-0

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