Cargando…

Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis

Plasma cytokines are biomarkers of disease extent and mycobacterial burden in pulmonary tuberculosis (PTB). Whether chemokines can perform the same role in PTB is not known. We examined the plasma levels of chemokines in individuals with PTB, latent TB (LTB) or healthy controls (HC) and their associ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Nathella P., Moideen, Kadar, Nancy, Arul, Viswanathan, Vijay, Shruthi, Basavaradhya S., Sivakumar, Shanmugam, Natarajan, Mohan, Kornfeld, Hardy, Babu, Subash
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890773/ https://www.ncbi.nlm.nih.gov/pubmed/31796883 http://dx.doi.org/10.1038/s41598-019-54803-w

Ejemplares similares

Plasma Eicosanoid Levels in Tuberculosis and Tuberculosis-Diabetes Co-morbidity Are Associated With Lung Pathology and Bacterial Burden
por: Pavan Kumar, Nathella, et al.
Publicado: (2019)

Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy
por: Kumar, Nathella Pavan, et al.
Publicado: (2019)

Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment
por: Kumar, Nathella P., et al.
Publicado: (2018)

Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Acute Phase Proteins Are Baseline Predictors of Tuberculosis Treatment Failure
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Heightened circulating levels of antimicrobial peptides in tuberculosis—Diabetes co-morbidity and reversal upon treatment
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Association of Plasma Matrix Metalloproteinase and Tissue Inhibitors of Matrix Metalloproteinase Levels With Adverse Treatment Outcomes Among Patients With Pulmonary Tuberculosis
por: Kumar, Nathella P., et al.
Publicado: (2020)

Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity
por: Kumar, Nathella Pavan, et al.
Publicado: (2019)

Chitinase and indoleamine 2, 3-dioxygenase are prognostic biomarkers for unfavorable treatment outcomes in pulmonary tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

Low body mass index is associated with diminished plasma cytokines and chemokines in both active and latent tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

Prediabetes is associated with the modulation of antigen-specific Th1/Tc1 and Th17/Tc17 responses in latent Mycobacterium tuberculosis infection
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Decreased Frequencies of Gamma/Delta T Cells Expressing Th1/Th17 Cytokine, Cytotoxic, and Immune Markers in Latent Tuberculosis-Diabetes/Pre-Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2021)

High Dimensionality Reduction and Immune Phenotyping of Natural Killer and Invariant Natural Killer Cells in Latent Tuberculosis-Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2022)

Altered systemic levels of acute phase proteins in tuberculous lymphadenitis and modulation after treatment
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2020)

Multi-Dimensionality Immunophenotyping Analyses of MAIT Cells Expressing Th1/Th17 Cytokines and Cytotoxic Markers in Latent Tuberculosis Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2022)

IL-27 and TGFβ mediated expansion of Th1 and adaptive regulatory T cells expressing IL-10 correlates with bacterial burden and disease severity in pulmonary tuberculosis
por: Kumar, Nathella P, et al.
Publicado: (2015)

Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications
por: Prada-Medina, Cesar A., et al.
Publicado: (2017)

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Are Potential Biomarkers of Pulmonary and Extra-Pulmonary Tuberculosis
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2020)

Coincident Pre-Diabetes Is Associated with Dysregulated Cytokine Responses in Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2014)

Immune Profiles in Multisystem Inflammatory Syndrome in Children with Cardiovascular Abnormalities
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

Randomized Trial of Metformin With Anti-Tuberculosis Drugs for Early Sputum Conversion in Adults With Pulmonary Tuberculosis
por: Padmapriydarsini, Chandrasekaran, et al.
Publicado: (2021)

Diminished Frequencies of Cytotoxic Marker Expressing T- and NK Cells at the Site of Mycobacterium tuberculosis Infection
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2020)

Reduced neutrophil granular proteins and post-treatment modulation in tuberculous lymphadenitis
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2021)

Systemic Levels of Pro-Inflammatory Cytokines and Post-Treatment Modulation in Tuberculous Lymphadenitis
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2023)

Prime-Boost Vaccination With Covaxin/BBV152 Induces Heightened Systemic Cytokine and Chemokine Responses
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Filarial Coinfection Is Associated With Higher Bacterial Burdens and Altered Plasma Cytokine and Chemokine Responses in Tuberculous Lymphadenitis
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2020)

Helminth Coinfection Is Associated With Enhanced Plasma Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Tuberculous Lymphadenitis
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2021)

Effect of SARS-CoV-2 seropositivity on antigen – specific cytokine and chemokine responses in latent tuberculosis
por: Rajamanickam, Anuradha, et al.
Publicado: (2022)

Enhanced SARS-CoV-2-Specific CD4(+) T Cell Activation and Multifunctionality in Late Convalescent COVID-19 Individuals
por: Pavan Kumar, Nathella, et al.
Publicado: (2022)

Altered circulating levels of B cell growth factors and their modulation upon anti-tuberculosis treatment in pulmonary tuberculosis and tuberculous lymphadenitis
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2018)

Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2016)

Plasma chemokines as immune biomarkers for diagnosis of pediatric tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Impact of diabetes mellitus on immunity to latent tuberculosis infection
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

Proteomics: A new perspective for cancer
por: Shruthi, Basavaradhya Sahukar, et al.
Publicado: (2016)

Decreased Prevalence of Lymphatic Filariasis among Diabetic Subjects Associated with a Diminished Pro-Inflammatory Cytokine Response (CURES 83)
por: Aravindhan, Vivekanandhan, et al.
Publicado: (2010)

A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction
por: Queiroz, Artur T. L., et al.
Publicado: (2023)

Differential Frequencies of Intermediate Monocyte Subsets Among Individuals Infected With Drug-Sensitive or Drug-Resistant Mycobacterium tuberculosis
por: Sampath, Pavithra, et al.
Publicado: (2022)

NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection
por: Cheekatla, Satyanarayana Swamy, et al.
Publicado: (2016)

Predominant Determinants of Delayed Tuberculosis Sputum Conversion in Indonesia
por: Wardani, Dyah Wulan Sumekar Rengganis, et al.
Publicado: (2019)

Effect of BCG vaccination on proinflammatory responses in elderly individuals
por: Pavan Kumar, Nathella, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0es46o2f663jrl1rfgjdf1v06s