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A new bioluminescence-based tool for modulating target proteins in live cells
We have developed a new genetically encoded tool designed to generate reactive oxygen species (ROS) at target proteins in cultured cells; it is designed using firefly luciferase and photosensitiser protein KillerRed. Targeting this fusion protein, KillerFirefly, to F-actin in live cells and treatmen...
Autores principales: | Ishimoto, Tetsuya, Mori, Hisashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890795/ https://www.ncbi.nlm.nih.gov/pubmed/31796796 http://dx.doi.org/10.1038/s41598-019-54712-y |
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