NCS-1 Deficiency Affects mRNA Levels of Genes Involved in Regulation of ATP Synthesis and Mitochondrial Stress in Highly Vulnerable Substantia nigra Dopaminergic Neurons

Neuronal Ca(2+) sensor proteins (NCS) transduce changes in Ca(2+) homeostasis into altered signaling and neuronal function. NCS-1 activity has emerged as important for neuronal viability and pathophysiology. The progressive degeneration of dopaminergic (DA) neurons, particularly within the Substanti...

Descripción completa

Detalles Bibliográficos
Autores principales: Simons, Carsten, Benkert, Julia, Deuter, Nora, Poetschke, Christina, Pongs, Olaf, Schneider, Toni, Duda, Johanna, Liss, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890851/
https://www.ncbi.nlm.nih.gov/pubmed/31827421
http://dx.doi.org/10.3389/fnmol.2019.00252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890851/
https://www.ncbi.nlm.nih.gov/pubmed/31827421
http://dx.doi.org/10.3389/fnmol.2019.00252

Ejemplares similares