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NCS-1 Deficiency Affects mRNA Levels of Genes Involved in Regulation of ATP Synthesis and Mitochondrial Stress in Highly Vulnerable Substantia nigra Dopaminergic Neurons
Neuronal Ca(2+) sensor proteins (NCS) transduce changes in Ca(2+) homeostasis into altered signaling and neuronal function. NCS-1 activity has emerged as important for neuronal viability and pathophysiology. The progressive degeneration of dopaminergic (DA) neurons, particularly within the Substanti...
Autores principales: | Simons, Carsten, Benkert, Julia, Deuter, Nora, Poetschke, Christina, Pongs, Olaf, Schneider, Toni, Duda, Johanna, Liss, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890851/ https://www.ncbi.nlm.nih.gov/pubmed/31827421 http://dx.doi.org/10.3389/fnmol.2019.00252 |
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