Cargando…

A Network Pharmacology-Based Strategy For Predicting Active Ingredients And Potential Targets Of LiuWei DiHuang Pill In Treating Type 2 Diabetes Mellitus

BACKGROUND: Traditional Chinese medicine (TCM) formulations have proven to be advantageous in clinical treatment and prevention of disease. LiuWei DiHuang Pill (LWDH Pill) is a TCM that was employed to treat type 2 diabetes mellitus (T2DM). However, a holistic network pharmacology approach to unders...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Dan, Huang, Jian-Hua, Zhang, Zhe-Yu, Du, Qing, Peng, Wei-Jun, Yu, Rong, Zhang, Si-Fang, Zhang, Shui-Han, Qin, Yu-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890936/ https://www.ncbi.nlm.nih.gov/pubmed/31819371 http://dx.doi.org/10.2147/DDDT.S216644

Ejemplares similares

A Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of LiuWei DiHuang Pill in Treating Type 2 Diabetes Mellitus [Corrigendum]
por: He, Dan, et al.
Publicado: (2020)

Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
por: Zhu, Haiming, et al.
Publicado: (2012)

The Mechanisms of Improving IVF Outcomes of Liu-Wei-Di-Huang Pill Acting on DOR Patients
por: Xiao, Jimei, et al.
Publicado: (2020)

Mechanism of Liuwei Dihuang Pills in treating osteoporosis based on network pharmacology
por: Wang, Xiqoqiang, et al.
Publicado: (2023)

Study on the Mechanism of Liuwei Dihuang Pills in Treating Parkinson's Disease Based on Network Pharmacology
por: Lin, Dongtao, et al.
Publicado: (2021)

Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology
por: Zhu, Fuping, et al.
Publicado: (2023)

A GC-MS-Based Metabolomics Investigation of the Protective Effect of Liu-Wei-Di-Huang-Wan in Type 2 Diabetes Mellitus Mice
por: Huang, Jian-hua, et al.
Publicado: (2020)

The Role of Liuwei Dihuang Pills and Ginkgo Leaf Tablets in Treating Diabetic Complications
por: Zhao, Yue, et al.
Publicado: (2016)

Network pharmacology-based strategy to investigate pharmacological mechanism of Liuwei Dihuang Pill against postmenopausal osteoporosis
por: Wang, Qingchan, et al.
Publicado: (2022)

Network pharmacology and molecular docking approach to elucidate the mechanisms of Liuwei Dihuang pill in diabetic osteoporosis
por: Lu, Zhaoqi, et al.
Publicado: (2022)

Identification of the Active Compound of Liu Wei Di Huang Wan for Treatment of Gestational Diabetes Mellitus via Network Pharmacology and Molecular Docking
por: Xiong, Yunqi, et al.
Publicado: (2022)

DNA Extraction Protocol for Biological Ingredient Analysis of Liuwei Dihuang Wan
por: Cheng, Xinwei, et al.
Publicado: (2014)

A network pharmacological-based study of the mechanism of Liuwei Dihuang pill in the treatment of chronic kidney disease
por: Xie, Xi, et al.
Publicado: (2023)

Immunomodulatory effects of modified Liu-Wei-Di-Huang-Wan Traditional Chinese medicine on allergic asthmatic mice
por: Tsai, Jaw-Ji, et al.
Publicado: (2023)

Exploring the Molecular Mechanism of Liuwei Dihuang Pills for Treating Diabetic Nephropathy by Combined Network Pharmacology and Molecular Docking
por: Wang, Gaoxiang, et al.
Publicado: (2021)

Effects of the Chinese Herbal Formulation (Liu Wei Di Huang Wan) on the Pharmacokinetics of Isoflavones in Postmenopausal Women
por: Limopasmanee, Wirin, et al.
Publicado: (2015)

Prediction of network pharmacology and molecular docking-based strategy to determine potential pharmacological mechanism of Liuwei Dihuang pill against tinnitus
por: Wu, Zhongbiao, et al.
Publicado: (2022)

Multicomponent Analysis of Liuwei Dihuang Pills by a Single Marker Quantification Method and Chemometric Discrimination of Fingerprints
por: Yang, Lin, et al.
Publicado: (2023)

Liu Wei Di Huang Wan and the Delay of Insulin Use in Patients with Type 2 Diabetes in Taiwan: A Nationwide Study
por: Chen, Hsin-Hung, et al.
Publicado: (2021)

A randomized controlled clinical trial study protocol of Liuwei Dihuang pills in the adjuvant treatment of diabetic kidney disease
por: Liao, Tingting, et al.
Publicado: (2020)

Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice
por: Zhuang, Shan, et al.
Publicado: (2017)

Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Liuwei Dihuang Decoction Against Intervertebral Disc Degeneration
por: Zhang, Huihao, et al.
Publicado: (2021)

Liuwei Dihuang Pill Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis via TGF-β/Smad2/3 Pathway
por: Shu, Shi, et al.
Publicado: (2022)

Longevity Effect of Liuwei Dihuang in Both Caenorhabditis Elegans and Aged Mice
por: Chen, Weidong, et al.
Publicado: (2019)

Research on the Mechanism of Liuwei Dihuang Decoction for Osteoporosis Based on Systematic Biological Strategies
por: Long, Zhi-yong, et al.
Publicado: (2022)

Liuwei Dihuang pill treats diabetic nephropathy in rats by inhibiting of TGF-β/SMADS, MAPK, and NF-kB and upregulating expression of cytoglobin in renal tissues
por: Xu, Zhong Ju, et al.
Publicado: (2017)

Biological ingredient analysis of traditional Chinese medicine preparation based on high-throughput sequencing: the story for Liuwei Dihuang Wan
por: Cheng, Xinwei, et al.
Publicado: (2014)

Liuwei Dihuang Decoction for primary osteoporosis: A protocol for a systematic review and meta-analysis
por: Liu, Yu, et al.
Publicado: (2019)

Predicting new indications of compounds with a network pharmacology approach: Liuwei Dihuang Wan as a case study
por: Wang, Yin-Ying, et al.
Publicado: (2017)

Liuwei Dihuang Pills Enhance the Effect of Western Medicine in Treating Diabetic Nephropathy: A Meta-Analysis of Randomized Controlled Trials
por: Lin, Lan, et al.
Publicado: (2016)

Bioinformatics-Based Approach for Exploring the Immune Cell Infiltration Patterns in Alzheimer’s Disease and Determining the Intervention Mechanism of Liuwei Dihuang Pill
por: Zhao, Chenling, et al.
Publicado: (2022)

Identification of Potential Molecular Targets and Active Ingredients of Mingmu Dihuang Pill for the Treatment of Diabetic Retinopathy Based on Network Pharmacology
por: Zhou, Yini, et al.
Publicado: (2022)

Liuwei Dihuang Lowers Body Weight and Improves Insulin and Leptin Sensitivity in Obese Rats
por: Perry, Benjamin, et al.
Publicado: (2012)

Liuwei Dihuang pill cures postmenopausal osteoporosis with kidney-Yin deficiency: Potential therapeutic targets identified based on gene expression profiling
por: Xu, Feng, et al.
Publicado: (2018)

Retracted: Liuwei Dihuang Pill Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis via TGF-β/Smad2/3 Pathway
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Exploring the Pharmacological Mechanism of Liuwei Dihuang Decoction for Diabetic Retinopathy: A Systematic Biological Strategy-Based Research
por: Yuan, Mengxia, et al.
Publicado: (2021)

Protective Effects of Liu Wei Di Huang Wan on the Liver, Orbitofrontal Cortex Nissl Bodies, and Neurites in MSG+PH-Induced Liver Regeneration Rat Model
por: Zhao, Bin-Bin, et al.
Publicado: (2018)

Therapeutic potential of Liuwei Dihuang pill against KDM7A and Wnt/β-catenin signaling pathway in diabetic nephropathy-related osteoporosis
por: Liu, Ming Ming, et al.
Publicado: (2020)

Liuwei Dihuang Pills Inhibit Podocyte Injury and Alleviate IgA Nephropathy by Directly Altering Mesangial Cell-Derived Exosome Function and Secretion
por: Zhu, Xiaodong, et al.
Publicado: (2022)

Corrigendum to “Exploring the Pharmacological Mechanism of Liuwei Dihuang Decoction for Diabetic Retinopathy: A Systematic Biological Strategy-Based Research”
por: Yuan, Mengxia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2mr1cc95onk9qe3jdg43kaipe7