Cargando…

Interferon-Responsive Genes Are Targeted during the Establishment of Human Cytomegalovirus Latency

Human cytomegalovirus (HCMV) latency is an active process which remodels the latently infected cell to optimize latent carriage and reactivation. This is achieved, in part, through the expression of viral genes, including the G-protein-coupled receptor US28. Here, we use an unbiased proteomic screen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elder, Elizabeth G., Krishna, Benjamin A., Williamson, James, Lim, Eleanor Y., Poole, Emma, Sedikides, George X., Wills, Mark, O’Connor, Christine M., Lehner, Paul J., Sinclair, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890990/ https://www.ncbi.nlm.nih.gov/pubmed/31796538 http://dx.doi.org/10.1128/mBio.02574-19

Ejemplares similares

Human Cytomegalovirus Upregulates Expression of HCLS1 Resulting in Increased Cell Motility and Transendothelial Migration during Latency
por: Aslam, Yusuf, et al.
Publicado: (2019)

Sleepless latency of human cytomegalovirus
por: Poole, Emma, et al.
Publicado: (2015)

Regulation of host and viral promoters during human cytomegalovirus latency via US28 and CTCF
por: Elder, Elizabeth G., et al.
Publicado: (2021)

Cytomegalovirus (CMV) Infection and Latency
por: O’Connor, Christine M.
Publicado: (2021)

Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection
por: Krishna, Benjamin A., et al.
Publicado: (2017)

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells
por: Jackson, Sarah E., et al.
Publicado: (2017)

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing
por: Shnayder, Miri, et al.
Publicado: (2018)

Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells
por: Krishna, B. A., et al.
Publicado: (2016)

Monocytes Latently Infected with Human Cytomegalovirus Evade Neutrophil Killing
por: Elder, Elizabeth, et al.
Publicado: (2019)

Human Cytomegalovirus Latency-Associated Proteins Elicit Immune-Suppressive IL-10 Producing CD4(+) T Cells
por: Mason, Gavin M., et al.
Publicado: (2013)

Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention
por: Groves, Ian J., et al.
Publicado: (2021)

The Requirement for US28 During Cytomegalovirus Latency Is Independent of US27 and US29 Gene Expression
por: Krishna, Benjamin A., et al.
Publicado: (2020)

The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression
por: Poole, Emma, et al.
Publicado: (2023)

A BMPR2/YY1 Signaling Axis Is Required for Human Cytomegalovirus Latency in Undifferentiated Myeloid Cells
por: Poole, Emma, et al.
Publicado: (2021)

Modulation of host cell signaling during cytomegalovirus latency and reactivation
por: Smith, Nicholas A., et al.
Publicado: (2021)

Latency-associated upregulation of SERBP1 is important for the recruitment of transcriptional repressors to the viral major immediate early promoter of human cytomegalovirus during latent carriage
por: Poole, Emma, et al.
Publicado: (2022)

Generation, maintenance and tissue distribution of T cell responses to human cytomegalovirus in lytic and latent infection
por: Jackson, Sarah E., et al.
Publicado: (2019)

A Virally Encoded DeSUMOylase Activity Is Required for Cytomegalovirus Reactivation from Latency
por: Poole, Emma L., et al.
Publicado: (2018)

Latency-Associated Viral Interleukin-10 (IL-10) Encoded by Human Cytomegalovirus Modulates Cellular IL-10 and CCL8 Secretion during Latent Infection through Changes in the Cellular MicroRNA hsa-miR-92a
por: Poole, Emma, et al.
Publicado: (2014)

Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation
por: Jackson, Sarah E., et al.
Publicado: (2021)

Understanding HCMV Latency Using Unbiased Proteomic Analyses
por: Poole, Emma, et al.
Publicado: (2020)

Cytomegalovirus US28 regulates cellular EphA2 to maintain viral latency
por: Wass, Amanda B., et al.
Publicado: (2022)

Reversible Silencing of Cytomegalovirus Genomes by Type I Interferon Governs Virus Latency
por: Dağ, Franziska, et al.
Publicado: (2014)

IL-10-Secreting CD8(+) T Cells Specific for Human Cytomegalovirus (HCMV): Generation, Maintenance and Phenotype
por: Jackson, Sarah E., et al.
Publicado: (2022)

The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6
por: Lau, Betty, et al.
Publicado: (2016)

Advances in the treatment of cytomegalovirus
por: Krishna, B A, et al.
Publicado: (2019)

Corrigendum: The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6
por: Lau, Betty, et al.
Publicado: (2016)

HCMV latency: what regulates the regulators?
por: Elder, Elizabeth, et al.
Publicado: (2019)

Diverse effects of interferon alpha on the establishment and reversal of HIV latency
por: Van der Sluis, Renée M., et al.
Publicado: (2020)

Regulation of Human Cytomegalovirus Transcription in Latency: Beyond the Major Immediate-Early Promoter
por: Reeves, Matthew, et al.
Publicado: (2013)

Interferon Alpha Induces Establishment of Alphaherpesvirus Latency in Sensory Neurons In Vitro
por: De Regge, Nick, et al.
Publicado: (2010)

Epigenetic Control of Cytomegalovirus Latency and Reactivation
por: Liu, Xue-feng, et al.
Publicado: (2013)

Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies
por: De Groof, Timo W. M., et al.
Publicado: (2021)

Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)–Seropositive Individuals Are Sites of HCMV Reactivation In Vivo
por: Poole, Emma, et al.
Publicado: (2015)

Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor
por: Perera, Marianne R, et al.
Publicado: (2022)

Regulation of the MIE Locus During HCMV Latency and Reactivation
por: Dooley, Abigail L., et al.
Publicado: (2020)

Molecular Determinants and the Regulation of Human Cytomegalovirus Latency and Reactivation
por: Collins-McMillen, Donna, et al.
Publicado: (2018)

Regulation of Latency and Reactivation by Human Cytomegalovirus miRNAs
por: Diggins, Nicole L., et al.
Publicado: (2021)

Advances in Model Systems for Human Cytomegalovirus Latency and Reactivation
por: Crawford, Lindsey B., et al.
Publicado: (2022)

Depletion of Cellular Pre-Replication Complex Factors Results in Increased Human Cytomegalovirus DNA Replication
por: Evans Braun, Tamara, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vm47bfjak7c5ntss3hhkki30vb