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Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography
A specific radioligand for the imaging of cyclic nucleotide phosphodiesterase 2A (PDE2A) via positron emission tomography (PET) would be helpful for research on the physiology and disease-related changes in the expression of this enzyme in the brain. In this report, the radiosynthesis of a novel PDE...
Autores principales: | Ritawidya, Rien, Wenzel, Barbara, Teodoro, Rodrigo, Toussaint, Magali, Kranz, Mathias, Deuther-Conrad, Winnie, Dukic-Stefanovic, Sladjana, Ludwig, Friedrich-Alexander, Scheunemann, Matthias, Brust, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891464/ https://www.ncbi.nlm.nih.gov/pubmed/31731831 http://dx.doi.org/10.3390/molecules24224149 |
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