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Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography

A specific radioligand for the imaging of cyclic nucleotide phosphodiesterase 2A (PDE2A) via positron emission tomography (PET) would be helpful for research on the physiology and disease-related changes in the expression of this enzyme in the brain. In this report, the radiosynthesis of a novel PDE...

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Detalles Bibliográficos
Autores principales: Ritawidya, Rien, Wenzel, Barbara, Teodoro, Rodrigo, Toussaint, Magali, Kranz, Mathias, Deuther-Conrad, Winnie, Dukic-Stefanovic, Sladjana, Ludwig, Friedrich-Alexander, Scheunemann, Matthias, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891464/
https://www.ncbi.nlm.nih.gov/pubmed/31731831
http://dx.doi.org/10.3390/molecules24224149

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