Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides

Homonucleoside analogues cis-16 and trans-17 having a (5-methoxycarbonyl)isoxazolidine framework were synthesized via the 1,3-dipolar cycloaddition of nucleobase-derived nitrones with methyl acrylate. Hydrogenolysis of the isoxazolidines containing thymine, dihydrouracil, theophylline and adenine mo...

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Detalles Bibliográficos
Autores principales: Piotrowska, Dorota G., Głowacka, Iwona E., Schols, Dominique, Snoeck, Robert, Andrei, Graciela, Gotkowska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891762/
https://www.ncbi.nlm.nih.gov/pubmed/31698778
http://dx.doi.org/10.3390/molecules24224014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891762/
https://www.ncbi.nlm.nih.gov/pubmed/31698778
http://dx.doi.org/10.3390/molecules24224014

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