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Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides

Homonucleoside analogues cis-16 and trans-17 having a (5-methoxycarbonyl)isoxazolidine framework were synthesized via the 1,3-dipolar cycloaddition of nucleobase-derived nitrones with methyl acrylate. Hydrogenolysis of the isoxazolidines containing thymine, dihydrouracil, theophylline and adenine mo...

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Detalles Bibliográficos
Autores principales:	Piotrowska, Dorota G., Głowacka, Iwona E., Schols, Dominique, Snoeck, Robert, Andrei, Graciela, Gotkowska, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891762/ https://www.ncbi.nlm.nih.gov/pubmed/31698778 http://dx.doi.org/10.3390/molecules24224014

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