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Modulation of Doxorubicin Intracellular Accumulation and Anticancer Activity by Triterpene Glycoside Cucumarioside A(2)-2

The effect of treatment of Ehrlich ascites carcinoma (EAC) cells with multidrug resistance by holothurian triterpene glycoside, cucumarioside A(2)-2 (CA(2)-2) was evaluated. Calcein-AM efflux assay and doxorubicin (DOX) uptake and retention measurement in cancer cells, as well as determination of DO...

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Detalles Bibliográficos
Autores principales:	Menchinskaya, Ekaterina, Gorpenchenko, Tatiana, Silchenko, Alexandra, Avilov, Sergey, Aminin, Dmitry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891776/ https://www.ncbi.nlm.nih.gov/pubmed/31652808 http://dx.doi.org/10.3390/md17110597

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