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Dynamic Profiling of Antitumor Activity of CAR T Cells Using Micropatterned Tumor Arrays
Cancer immunotherapy based on the engineering of chimeric antigen receptors (CAR) on T cells has emerged as one of the most promising new therapies for patients with B‐cell malignancies. Preclinical assessments of essential CAR T cell functions such as trafficking and cytotoxicity are critical for a...
Autores principales: | Wang, Xiao, Scarfò, Irene, Schmidts, Andrea, Toner, Mehmet, Maus, Marcela V., Irimia, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891905/ https://www.ncbi.nlm.nih.gov/pubmed/31832320 http://dx.doi.org/10.1002/advs.201901829 |
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