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IgA1 deposition may induce NLRP3 expression and macrophage transdifferentiation of podocyte in IgA nephropathy

BACKGROUND: The NLRP3 inflammasome plays an important role in mediating podocyte injury in various kidney diseases. The aim of this study was to investigate whether NLRP3 expression associated with podocyte injury was involved in the pathogenesis of IgA nephropathy (IgAN). METHODS: NLRP3 inflammasom...

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Detalles Bibliográficos
Autores principales:	Peng, Wei, Pei, Gai-qin, Tang, Yi, Tan, Li, Qin, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891954/ https://www.ncbi.nlm.nih.gov/pubmed/31796125 http://dx.doi.org/10.1186/s12967-019-02157-2

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