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Estrogen stimulates SREBP2 expression in hepatic cell lines via an estrogen response element in the SREBP2 promoter

OBJECTIVE: Hypoestrogenism in women is strongly associated with menopause and it can lead to lipid disorder, which predisposes people to premature cardiovascular disease. However, the mechanism of lipid disorder remains unclear. Sterol regulatory element-binding protein 2 (SREBP2) is the key transcr...

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Detalles Bibliográficos
Autores principales: Meng, Ye, Zong, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892134/
https://www.ncbi.nlm.nih.gov/pubmed/31827541
http://dx.doi.org/10.1186/s11658-019-0194-5