Cargando…

A model for determining cardiac mitochondrial substrate utilisation using stable (13)C-labelled metabolites

INTRODUCTION: Relative oxidation of different metabolic substrates in the heart varies both physiologically and pathologically, in order to meet metabolic demands under different circumstances. (13)C labelled substrates have become a key tool for studying substrate use—yet an accurate model is requi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lindsay, Ross T., Demetriou, Demetris, Manetta-Jones, Dominic, West, James A., Murray, Andrew J., Griffin, Julian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892366/ https://www.ncbi.nlm.nih.gov/pubmed/31773381 http://dx.doi.org/10.1007/s11306-019-1618-y

Ejemplares similares

β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery
por: Lindsay, Ross T, et al.
Publicado: (2021)

Direct arterial injection of hyperpolarized (13)C‐labeled substrates into rat tumors for rapid MR detection of metabolism with minimal substrate dilution
por: Reynolds, Steven, et al.
Publicado: (2017)

Ethyl Pyruvate Increases Post-Ischemic Levels of Mitochondrial Energy Metabolites: A (13)C-Labeled Cerebral Microdialysis Study
por: Nygaard, Kevin H., et al.
Publicado: (2020)

Substrate utilisation of cultured skeletal muscle cells in patients with CFS
por: Tomas, Cara, et al.
Publicado: (2020)

Mitochondrial responses to extreme environments: insights from metabolomics
por: O’Brien, Katie A, et al.
Publicado: (2015)

Stable Isotope Phosphate Labelling of Diverse Metabolites is Enabled by a Family of (18)O‐Phosphoramidites
por: Haas, Thomas M., et al.
Publicado: (2021)

Utilisation and Off-Label Prescriptions of Respiratory Drugs in Children
por: Schmiedl, Sven, et al.
Publicado: (2014)

(13)C labeling dynamics of intra- and extracellular metabolites in CHO suspension cells
por: Wahrheit, Judith, et al.
Publicado: (2013)

In Vivo Microdialysis of Endogenous and (13)C-labeled TCA Metabolites in Rat Brain: Reversible and Persistent Effects of Mitochondrial Inhibition and Transient Cerebral Ischemia
por: Havelund, Jesper F., et al.
Publicado: (2019)

Gas Chromatography Mass Spectrometry (GC-MS) Quantification of Metabolites in Stool Using (13)C Labelled Compounds
por: Gould, Oliver, et al.
Publicado: (2018)

Competition Triggers Plasmid-Mediated Enhancement of Substrate Utilisation in Pseudomonas putida
por: Joshi, Hiren, et al.
Publicado: (2009)

Influence of phenolic substrates utilised by yeast Trichosporon cutaneum on the degradation kinetics
por: Gerginova, Maria, et al.
Publicado: (2014)

The Effects of Pre-Game Carbohydrate Intake on Running Performance and Substrate Utilisation during Simulated Gaelic Football Match Play
por: O’Brien, Luke, et al.
Publicado: (2021)

Bacterial dominance is due to effective utilisation of secondary metabolites produced by competitors
por: Morgan, Benjamin G., et al.
Publicado: (2020)

Interpretation of non-invasive breath tests using (13)C-labeled substrates - a preliminary report with (13)C-methacetin
por: Lock, JF, et al.
Publicado: (2009)

Determination of thiol metabolites in human urine by stable isotope labeling in combination with pseudo-targeted mass spectrometry analysis
por: Liu, Ping, et al.
Publicado: (2016)

Metabolic rate and substrate utilisation resilience in men undertaking polar expeditionary travel
por: Hattersley, John, et al.
Publicado: (2019)

The effects of environmental hypoxia on substrate utilisation during exercise: a meta-analysis
por: Griffiths, Alex, et al.
Publicado: (2019)

Identification of an Epoxide Metabolite of Lycopene in Human Plasma Using (13)C-Labeling and QTOF-MS
por: Cichon, Morgan J., et al.
Publicado: (2018)

Bacillus pumilus laccase: a heat stable enzyme with a wide substrate spectrum
por: Reiss, Renate, et al.
Publicado: (2011)

Untargeted Profiling of Tracer-Derived Metabolites Using Stable Isotopic Labeling and Fast Polarity-Switching LC–ESI-HRMS
por: Kluger, Bernhard, et al.
Publicado: (2014)

The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety
por: Smeets, Astrid J., et al.
Publicado: (2009)

Substrate Utilisation and Energy Metabolism in Non-Growing Campylobacter jejuni M1cam
por: Stoakes, Emily, et al.
Publicado: (2022)

Systematic NMR Analysis of Stable Isotope Labeled Metabolite Mixtures in Plant and Animal Systems: Coarse Grained Views of Metabolic Pathways
por: Chikayama, Eisuke, et al.
Publicado: (2008)

DExSI: a new tool for the rapid quantitation of (13)C-labelled metabolites detected by GC-MS
por: Dagley, Michael J, et al.
Publicado: (2018)

Economical Synthesis of (13)C-Labeled Opiates, Cocaine Derivatives and Selected Urinary Metabolites by Derivatization of the Natural Products
por: Karlsen, Morten, et al.
Publicado: (2015)

Selfish, sharing and scavenging bacteria in the Atlantic Ocean: a biogeographical study of bacterial substrate utilisation
por: Reintjes, Greta, et al.
Publicado: (2018)

Acute Effects of Whole-Body Vibration on Resting Metabolic Rate and Substrate Utilisation in Healthy Women
por: Maciejczyk, Marcin, et al.
Publicado: (2022)

Trimethyl Lock: A Stable Chromogenic Substrate for Esterases
por: Levine, Michael N., et al.
Publicado: (2008)

Expertise paradigms for investigating the neural substrates of stable memories
por: Campitelli, Guillermo, et al.
Publicado: (2013)

Probing rapid carbon fixation in fast-growing seaweed Ulva meridionalis using stable isotope (13)C-labelling
por: Tsubaki, Shuntaro, et al.
Publicado: (2020)

Antiviral drug Triazavirin, selectively labeled with (2)H, (13)C, and (15)N stable isotopes. Synthesis and properties
por: Shestakova, Tatyana S., et al.
Publicado: (2021)

Authentication of Iranian Saffron (Crocus sativus) Using Stable Isotopes δ(13)C and δ(2)H and Metabolites Quantification
por: Moras, Benjamin, et al.
Publicado: (2022)

Stable beams at 13 TeV
Publicado: (2015)

Stable beams at 13 TeV
Publicado: (2015)

Stable beams at 13 TeV
Publicado: (2015)

Utilisation of drugs for the treatment of psychiatric diseases in the pediatric population: focus on off-label use
por: Pesiou, Stella, et al.
Publicado: (2023)

Correction: Systematic NMR Analysis of Stable Isotope Labeled Metabolite Mixtures in Plant and Animal Systems: Coarse Grained Views of Metabolic Pathways
por: Chikayama, Eisuke, et al.
Publicado: (2009)

Correction: Systematic NMR Analysis of Stable Isotope Labeled Metabolite Mixtures in Plant and Animal Systems: Coarse Grained Views of Metabolic Pathways
por: Chikayama, Eisuke, et al.
Publicado: (2009)

Stable Isotope Labeling with Amino acids in Nematodes
por: Larance, Mark, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_m5edsb2t4s91dkr0pcdfdpm078