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Cx3cr1-deficient microglia exhibit a premature aging transcriptome
CX3CR1, one of the highest expressed genes in microglia in mice and humans, is implicated in numerous microglial functions. However, the molecular mechanisms underlying Cx3cr1 signaling are not well understood. Here, we analyzed transcriptomes of Cx3cr1-deficient microglia under varying conditions b...
Autores principales: | Gyoneva, Stefka, Hosur, Raghavendra, Gosselin, David, Zhang, Baohong, Ouyang, Zhengyu, Cotleur, Anne C, Peterson, Michael, Allaire, Norm, Challa, Ravi, Cullen, Patrick, Roberts, Chris, Miao, Kelly, Reynolds, Taylor L, Glass, Christopher K, Burkly, Linda, Ransohoff, Richard M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892408/ https://www.ncbi.nlm.nih.gov/pubmed/31792059 http://dx.doi.org/10.26508/lsa.201900453 |
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