Recruitment of the Ulp2 protease to the inner kinetochore prevents its hyper-sumoylation to ensure accurate chromosome segregation

The kinetochore is the central molecular machine that drives chromosome segregation in all eukaryotes. Genetic studies have suggested that protein sumoylation plays a role in regulating the inner kinetochore; however, the mechanism remains elusive. Here, we show that Saccharomyces cerevisiae Ulp2, a...

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Detalles Bibliográficos
Autores principales: Suhandynata, Raymond T., Quan, Yun, Yang, Yusheng, Yuan, Wei-Tsung, Albuquerque, Claudio P., Zhou, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892545/
https://www.ncbi.nlm.nih.gov/pubmed/31747400
http://dx.doi.org/10.1371/journal.pgen.1008477

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