Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report

Hypercalcemia is a common paraneoplastic syndrome that is associated with many malignancies. Hypercalcemia develops in malignancies through various mechanisms. Parathyroid hormone-related protein (PTHrP) is secreted by malignancy involving the lungs, breast, colorectum, bladder, and, rarely, neuroen...

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Detalles Bibliográficos
Autores principales: Shaka, Hafeez, Raghavan, Sairam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892572/
https://www.ncbi.nlm.nih.gov/pubmed/31832292
http://dx.doi.org/10.7759/cureus.6075
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author Shaka, Hafeez
Raghavan, Sairam
author_facet Shaka, Hafeez
Raghavan, Sairam
author_sort Shaka, Hafeez
collection PubMed
description Hypercalcemia is a common paraneoplastic syndrome that is associated with many malignancies. Hypercalcemia develops in malignancies through various mechanisms. Parathyroid hormone-related protein (PTHrP) is secreted by malignancy involving the lungs, breast, colorectum, bladder, and, rarely, neuroendocrine tumors. This is a rare case of severe hypercalcemia as the initial presentation of a high-grade metastatic neuroendocrine tumor of an unknown primary site.
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spelling pubmed-68925722019-12-12 Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report Shaka, Hafeez Raghavan, Sairam Cureus Oncology Hypercalcemia is a common paraneoplastic syndrome that is associated with many malignancies. Hypercalcemia develops in malignancies through various mechanisms. Parathyroid hormone-related protein (PTHrP) is secreted by malignancy involving the lungs, breast, colorectum, bladder, and, rarely, neuroendocrine tumors. This is a rare case of severe hypercalcemia as the initial presentation of a high-grade metastatic neuroendocrine tumor of an unknown primary site. Cureus 2019-11-05 /pmc/articles/PMC6892572/ /pubmed/31832292 http://dx.doi.org/10.7759/cureus.6075 Text en Copyright © 2019, Shaka et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Shaka, Hafeez
Raghavan, Sairam
Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report
title Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report
title_full Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report
title_fullStr Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report
title_full_unstemmed Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report
title_short Severe Hypercalcemia as the Initial Presentation of a Neuroendocrine Carcinoma of Unknown Primary Site: A Case Report
title_sort severe hypercalcemia as the initial presentation of a neuroendocrine carcinoma of unknown primary site: a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892572/
https://www.ncbi.nlm.nih.gov/pubmed/31832292
http://dx.doi.org/10.7759/cureus.6075
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