Requirement for translocon-associated protein (TRAP) α in insulin biogenesis

The mechanistic basis for the biogenesis of peptide hormones and growth factors is poorly understood. Here, we show that the conserved endoplasmic reticulum membrane translocon-associated protein α (TRAPα), also known as signal sequence receptor 1, plays a critical role in the biosynthesis of insuli...

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Detalles Bibliográficos
Autores principales: Li, Xin, Itani, Omar A., Haataja, Leena, Dumas, Kathleen J., Yang, Jing, Cha, Jeeyeon, Flibotte, Stephane, Shih, Hung-Jen, Delaney, Colin E., Xu, Jialu, Qi, Ling, Arvan, Peter, Liu, Ming, Hu, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892615/
https://www.ncbi.nlm.nih.gov/pubmed/31840061
http://dx.doi.org/10.1126/sciadv.aax0292

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