Heparin Forms Polymers with Cell-free DNA Which Elongate Under Shear in Flowing Blood

Heparin is a widely used anticoagulant which inhibits factor Xa and thrombin through potentiation of antithrombin. We recently identified that the nucleic acid stain SYTOX reacts with platelet polyphosphate due to molecular similarities, some of which are shared by heparin. We attempted to study hep...

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Detalles Bibliográficos
Autores principales: de Vries, Joost C., Barendrecht, Arjan D., Clark, Chantal C., Urbanus, Rolf T., Boross, Peter, de Maat, Steven, Maas, Coen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892814/
https://www.ncbi.nlm.nih.gov/pubmed/31797980
http://dx.doi.org/10.1038/s41598-019-54818-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892814/
https://www.ncbi.nlm.nih.gov/pubmed/31797980
http://dx.doi.org/10.1038/s41598-019-54818-3

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