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Heparin Forms Polymers with Cell-free DNA Which Elongate Under Shear in Flowing Blood
Heparin is a widely used anticoagulant which inhibits factor Xa and thrombin through potentiation of antithrombin. We recently identified that the nucleic acid stain SYTOX reacts with platelet polyphosphate due to molecular similarities, some of which are shared by heparin. We attempted to study hep...
Autores principales: | de Vries, Joost C., Barendrecht, Arjan D., Clark, Chantal C., Urbanus, Rolf T., Boross, Peter, de Maat, Steven, Maas, Coen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892814/ https://www.ncbi.nlm.nih.gov/pubmed/31797980 http://dx.doi.org/10.1038/s41598-019-54818-3 |
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