Cargando…
Cell death following the loss of ADAR1 mediated A-to-I RNA editing is not effected by the intrinsic apoptosis pathway
Modifications of RNA, collectively termed as the epitranscriptome, are widespread, evolutionarily conserved and contribute to gene regulation and protein diversity in healthy and disease states. There are >160 RNA modifications described, greatly exceeding the number of modifications to DNA. Of t...
Autores principales: | Walkley, Carl R., Kile, Benjamin T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892865/ https://www.ncbi.nlm.nih.gov/pubmed/31801951 http://dx.doi.org/10.1038/s41419-019-2160-6 |
Ejemplares similares
-
Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs
por: Walkley, Carl R., et al.
Publicado: (2017) -
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis
por: Heraud-Farlow, Jacki E., et al.
Publicado: (2017) -
Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood
por: Ke, Francine F. S., et al.
Publicado: (2022) -
Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects
por: Keegan, Liam P., et al.
Publicado: (2011) -
ADAR1 is essential for maintenance of hematopoiesis and suppression of interferon signaling
por: Hartner, Jochen C., et al.
Publicado: (2008)