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Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3
Upon necroptosis activation, receptor interacting serine/threonine kinase (RIPK)1 and RIPK3 form a necrosome complex with pseudokinase mixed lineage kinase-like (MLKL). Although protein phosphorylation is a key event for RIPK1 and RIPK3 activation in response to a necroptosis signal, relatively litt...
Autores principales: | Lee, Song-Yi, Kim, Hyunjoo, Li, Cathena Meiling, Kang, Jaemin, Najafov, Ayaz, Jung, Muhah, Kang, Soosung, Wang, Shaomeng, Yuan, Junying, Jung, Yong-Keun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892881/ https://www.ncbi.nlm.nih.gov/pubmed/31801942 http://dx.doi.org/10.1038/s41419-019-2146-4 |
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