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Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer’s disease mouse model promotes synaptic resilience

Current approaches in treatment of Alzheimer’s disease (AD) is focused on early stages of cognitive decline. Identifying therapeutic targets that promote synaptic resilience during early stages may prevent progressive memory deficits by preserving memory mechanisms. We recently reported that the ind...

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Detalles Bibliográficos
Autores principales: Bourne, Krystyn Z., Natarajan, Chandramouli, Perez, Carlos X. Medina, Tumurbaatar, Batbayar, Taglialatela, Giulio, Krishnan, Balaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892889/
https://www.ncbi.nlm.nih.gov/pubmed/31797996
http://dx.doi.org/10.1038/s41598-019-54974-6