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Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α
The Warburg effect is a peculiar feature of cancer’s metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal tissue. Matrine is an alkaloid extracted from the herb root of a traditional Chinese medicine, Sophora flavescens Ait. Matrine has been reported...
Autores principales: | Hong, Xiaoting, Zhong, Linhai, Xie, Yurou, Zheng, Kaifeng, Pang, Jinglong, Li, Yesen, Yang, Yifan, Xu, Xiaolin, Mi, Panying, Cao, Hanwei, Zhang, Wenqing, Hu, Tianhui, Song, Gang, Wang, Daxuan, Zhan, Yan-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892950/ https://www.ncbi.nlm.nih.gov/pubmed/31849679 http://dx.doi.org/10.3389/fphar.2019.01437 |
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