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Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis
The regulation of the proliferation and polarity of neural progenitors is crucial for the development of the brain cortex. Animal studies have implicated glycogen synthase kinase 3 (GSK3) as a pivotal regulator of both proliferation and polarity, yet the functional relevance of its signaling for the...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893153/ https://www.ncbi.nlm.nih.gov/pubmed/31607568 http://dx.doi.org/10.1016/j.stemcr.2019.09.005 |