Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis

The regulation of the proliferation and polarity of neural progenitors is crucial for the development of the brain cortex. Animal studies have implicated glycogen synthase kinase 3 (GSK3) as a pivotal regulator of both proliferation and polarity, yet the functional relevance of its signaling for the...

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Detalles Bibliográficos
Autores principales: López-Tobón, Alejandro, Villa, Carlo Emanuele, Cheroni, Cristina, Trattaro, Sebastiano, Caporale, Nicolò, Conforti, Paola, Iennaco, Raffaele, Lachgar, Maria, Rigoli, Marco Tullio, Marcó de la Cruz, Berta, Lo Riso, Pietro, Tenderini, Erika, Troglio, Flavia, De Simone, Marco, Liste-Noya, Isabel, Macino, Giuseppe, Pagani, Massimiliano, Cattaneo, Elena, Testa, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893153/
https://www.ncbi.nlm.nih.gov/pubmed/31607568
http://dx.doi.org/10.1016/j.stemcr.2019.09.005

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