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Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathway

The present study was designed to investigate the protective effect of moracin on primary culture of nucleus pulposus cells in intervertebral disc and explore the underlying mechanism. Moracin treatment significantly inhibited the LPS-induced inflammatory cytokine accumulation (IL-1β, IL-6 and TNF-α...

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Detalles Bibliográficos
Autores principales: Gu, Ronghe, Huang, Zonggui, Liu, Huijiang, Qing, Qiwen, Zhuan, Zou, Yang, Lijing, Su, Zhongyi, Huang, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893166/
https://www.ncbi.nlm.nih.gov/pubmed/31729530
http://dx.doi.org/10.1042/BSR20191673