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Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast

Precise allele replacement (genome editing), without unwanted changes to the genome, provides a powerful tool to define the functions of DNA elements and encoded factors in their normal biological context. While CRISPR is now used extensively for gene targeting, its utility for precise allele replac...

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Detalles Bibliográficos
Autores principales:	Storey, Aaron J., Wang, Hsin-Ping, Protacio, Reine U., Davidson, Mari K., Wahls, Wayne P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2019
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893178/ https://www.ncbi.nlm.nih.gov/pubmed/31597677 http://dx.doi.org/10.1534/g3.119.400805

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