Natural Genetic Variation Screen in Drosophila Identifies Wnt Signaling, Mitochondrial Metabolism, and Redox Homeostasis Genes as Modifiers of Apoptosis

Apoptosis is the primary cause of degeneration in a number of neuronal, muscular, and metabolic disorders. These diseases are subject to a great deal of phenotypic heterogeneity in patient populations, primarily due to differences in genetic variation between individuals. This creates a barrier to e...

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Detalles Bibliográficos
Autores principales: Palu, Rebecca A. S., Ong, Elaine, Stevens, Kaitlyn, Chung, Shani, Owings, Katie G., Goodman, Alan G., Chow, Clement Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893197/
https://www.ncbi.nlm.nih.gov/pubmed/31570502
http://dx.doi.org/10.1534/g3.119.400722

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