Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review

Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidativ...

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Autores principales: Saji, Nancy, Francis, Nidhish, Schwarz, Lachlan J., Blanchard, Christopher L., Santhakumar, Abishek B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893409/
https://www.ncbi.nlm.nih.gov/pubmed/31718066
http://dx.doi.org/10.3390/nu11112736
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author Saji, Nancy
Francis, Nidhish
Schwarz, Lachlan J.
Blanchard, Christopher L.
Santhakumar, Abishek B.
author_facet Saji, Nancy
Francis, Nidhish
Schwarz, Lachlan J.
Blanchard, Christopher L.
Santhakumar, Abishek B.
author_sort Saji, Nancy
collection PubMed
description Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.
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spelling pubmed-68934092019-12-23 Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review Saji, Nancy Francis, Nidhish Schwarz, Lachlan J. Blanchard, Christopher L. Santhakumar, Abishek B. Nutrients Review Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases. MDPI 2019-11-12 /pmc/articles/PMC6893409/ /pubmed/31718066 http://dx.doi.org/10.3390/nu11112736 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Saji, Nancy
Francis, Nidhish
Schwarz, Lachlan J.
Blanchard, Christopher L.
Santhakumar, Abishek B.
Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review
title Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review
title_full Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review
title_fullStr Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review
title_full_unstemmed Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review
title_short Rice Bran Derived Bioactive Compounds Modulate Risk Factors of Cardiovascular Disease and Type 2 Diabetes Mellitus: An Updated Review
title_sort rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: an updated review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893409/
https://www.ncbi.nlm.nih.gov/pubmed/31718066
http://dx.doi.org/10.3390/nu11112736
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