α-Lactosylceramide Protects Against iNKT-Mediated Murine Airway Hyperreactivity and Liver Injury Through Competitive Inhibition of Cd1d Binding

Invariant natural killer T (iNKT) cells, which are activated by T cell receptor (TCR)-dependent recognition of lipid-based antigens presented by the CD1d molecule, have been shown to participate in the pathogenesis of many diseases, including asthma and liver injury. Previous studies have shown the...

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Detalles Bibliográficos
Autores principales: Lai, Alan Chuan-Ying, Chi, Po-Yu, Thio, Christina Li-Ping, Han, Yun-Chiann, Kao, Hsien-Neng, Hsieh, Hsiao-Wu, Gervay-Hague, Jacquelyn, Chang, Ya-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893574/
https://www.ncbi.nlm.nih.gov/pubmed/31850305
http://dx.doi.org/10.3389/fchem.2019.00811

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