Molecular Dynamics Simulation Reveals Exposed Residues in the Ligand-Binding Domain of the Low-Density Lipoprotein Receptor that Interacts with Vesicular Stomatitis Virus-G Envelope

Familial hypercholesterolemia (FH) is an autosomal dominant disease most often caused by mutations in the low-density lipoprotein receptor (LDLR) gene, which consists of 18 exons spanning 45 kb and codes for a precursor protein of 860 amino acids. Mutations in the LDLR gene lead to a reduced hepatic...

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Detalles Bibliográficos
Autores principales: Al-Allaf, Faisal A., Abduljaleel, Zainularifeen, Taher, Mohiuddin M., Abdellatif, Ahmed A. H., Athar, Mohammad, Bogari, Neda M., Al-Ahdal, Mohammed N., Al-Mohanna, Futwan, Al-Hassnan, Zuhair N., Alzabeedi, Kamal H. Y., Banssir, Talib M., Bouazzaoui, Abdellatif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893590/
https://www.ncbi.nlm.nih.gov/pubmed/31731579
http://dx.doi.org/10.3390/v11111063

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