Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches

One of the major neurodegenerative features of Alzheimer’s disease (AD) is the presence of neurotoxic amyloid plaques composed of amyloid beta peptide (Aβ). β-Secretase (BACE1) and acetylcholinesterase (AChE), which promote Aβ fibril formation, have become attractive therapeutic targets for AD. P-gl...

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Detalles Bibliográficos
Autores principales: Han, Jin, Ji, Yeongseon, Youn, Kumju, Lim, GyuTae, Lee, Jinhyuk, Kim, Dong Hyun, Jun, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893645/
https://www.ncbi.nlm.nih.gov/pubmed/31703329
http://dx.doi.org/10.3390/nu11112694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893645/
https://www.ncbi.nlm.nih.gov/pubmed/31703329
http://dx.doi.org/10.3390/nu11112694

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