Parechovirus A Pathogenesis and the Enigma of Genotype A-3

Parechovirus A is a species in the Parechovirus genus within the Picornaviridae family that can cause severe disease in children. Relatively little is known on Parechovirus A epidemiology and pathogenesis. This review aims to explore the Parechovirus A literature and highlight the differences betwee...

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Autores principales: Sridhar, Adithya, Karelehto, Eveliina, Brouwer, Lieke, Pajkrt, Dasja, Wolthers, Katja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893760/
https://www.ncbi.nlm.nih.gov/pubmed/31739613
http://dx.doi.org/10.3390/v11111062
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author Sridhar, Adithya
Karelehto, Eveliina
Brouwer, Lieke
Pajkrt, Dasja
Wolthers, Katja C.
author_facet Sridhar, Adithya
Karelehto, Eveliina
Brouwer, Lieke
Pajkrt, Dasja
Wolthers, Katja C.
author_sort Sridhar, Adithya
collection PubMed
description Parechovirus A is a species in the Parechovirus genus within the Picornaviridae family that can cause severe disease in children. Relatively little is known on Parechovirus A epidemiology and pathogenesis. This review aims to explore the Parechovirus A literature and highlight the differences between Parechovirus A genotypes from a pathogenesis standpoint. In particular, the curious case of Parechovirus-A3 and the genotype-specific disease association will be discussed. Finally, a brief outlook on Parechovirus A research is provided.
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spelling pubmed-68937602019-12-23 Parechovirus A Pathogenesis and the Enigma of Genotype A-3 Sridhar, Adithya Karelehto, Eveliina Brouwer, Lieke Pajkrt, Dasja Wolthers, Katja C. Viruses Review Parechovirus A is a species in the Parechovirus genus within the Picornaviridae family that can cause severe disease in children. Relatively little is known on Parechovirus A epidemiology and pathogenesis. This review aims to explore the Parechovirus A literature and highlight the differences between Parechovirus A genotypes from a pathogenesis standpoint. In particular, the curious case of Parechovirus-A3 and the genotype-specific disease association will be discussed. Finally, a brief outlook on Parechovirus A research is provided. MDPI 2019-11-14 /pmc/articles/PMC6893760/ /pubmed/31739613 http://dx.doi.org/10.3390/v11111062 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sridhar, Adithya
Karelehto, Eveliina
Brouwer, Lieke
Pajkrt, Dasja
Wolthers, Katja C.
Parechovirus A Pathogenesis and the Enigma of Genotype A-3
title Parechovirus A Pathogenesis and the Enigma of Genotype A-3
title_full Parechovirus A Pathogenesis and the Enigma of Genotype A-3
title_fullStr Parechovirus A Pathogenesis and the Enigma of Genotype A-3
title_full_unstemmed Parechovirus A Pathogenesis and the Enigma of Genotype A-3
title_short Parechovirus A Pathogenesis and the Enigma of Genotype A-3
title_sort parechovirus a pathogenesis and the enigma of genotype a-3
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893760/
https://www.ncbi.nlm.nih.gov/pubmed/31739613
http://dx.doi.org/10.3390/v11111062
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