Characterization of folate receptor alpha (FRα) expression in archival tumor and biopsy samples from relapsed epithelial ovarian cancer patients: A phase I expansion study of the FRα-targeting antibody-drug conjugate mirvetuximab soravtansine

PURPOSE. To characterize folate receptor alpha (FRα) expression in archival and fresh biopsy tumor samples from relapsed ovarian cancer patients. METHODS. Patients with ovarian tumors amenable to biopsy were eligible to enroll. Eligibility included a minimum requirement of FRα positivity in archival...

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Detalles Bibliográficos
Autores principales: Martin, Lainie P., Konner, Jason A., Moore, Kathleen N., Seward, Shelly M., Matulonis, Ursula A., Perez, Raymond P., Su, Ying, Berkenblit, Anna, Ruiz-Soto, Rodrigo, Birrer, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893864/
https://www.ncbi.nlm.nih.gov/pubmed/28843653
http://dx.doi.org/10.1016/j.ygyno.2017.08.015

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