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Human induced pluripotent stem cells from two azoospermic patients with Klinefelter syndrome show similar X chromosome inactivation behavior to female pluripotent stem cells

STUDY QUESTION: Does the X chromosome inactivation (XCI) of Klinefelter syndrome (KS)-derived human induced pluripotent stem cells (hiPSCs) correspond to female human pluripotent stem cells (hPSCs) and reflect the KS genotype? SUMMARY ANSWER: Our results demonstrate for the first time that KS-derive...

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Detalles Bibliográficos
Autores principales:	Panula, Sarita, Kurek, Magdalena, Kumar, Pankaj, Albalushi, Halima, Padrell Sánchez, Sara, Damdimopoulou, Pauliina, Olofsson, Jan I, Hovatta, Outi, Lanner, Fredrik, Stukenborg, Jan-Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894010/ https://www.ncbi.nlm.nih.gov/pubmed/31743397 http://dx.doi.org/10.1093/humrep/dez134

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